Why is my vagina painful?
Why is my anal and vagina painful and I started the arvs yesterday?
ARVs (antiretroviral medications) are not known to cause anal or vaginal pain as one of the side-effects. As you only started the medications yesterday I do not think it is likely to be related to the pain. I suggest you continue the medications but arrange to see your doctor for an examination. It is possible that there is something else going on (such as thrush or herpes) causing the pain in this area and it may need treatment.